WADA Prohibited List

The Prohibited List is updated annually following an extensive consultation process facilitated by WADA. Additional substances or methods may be added to the List at any time during the year but this will only occur after a three month notice period.

The World Anti-Doping Agency (WADA) has published the 2019 List of Prohibited Substances and Methods, which will come into effect on 1 January.

Here are the key things you need to know about the 2019 WADA Prohibited List:

Check your supplements carefully

  • Epiandrosterone has been added as an example of a steroid, which can be found in some dietary supplements.
  • The examples of metabolites of steroids which the body does not naturally produce has been simplified. It now only includes those known to be found in supplements or used as masking agents.
  • More examples of substances which were already prohibited have been added, and these can be found in some supplements, so don’t get caught out. 4-methylpentan-2-amine has been included as another name for DMBA, while 5-methylhexan-2-amine (1,4-dimethylpentylamine) and 3-methylhexan-2-amine (1,2-dimethylpentylamine) were added as examples of substances related to methylhexaneamine.


Don’t let strange names catch you out

  • The following names for substances which were already on the Prohibited List (in brackets below) have been added, so please check ingredients carefully as these may crop up.
  • Dimetamfetamine (dimethylamphetamine)
  • Enobosarm (ostarine)
  • Examorelin (hexarelin)
  • Lenomorelin (ghrelin)
  • More examples of prohibited substances have also been added.
  • Daprodustat (GSK1278863) and vadadustat (AKB-6548) – examples of hypoxia inducible factor (HIF) activating agents.
  • BAY 85-3934 – reference name of molidustat, a HIF activating agent.
  • Macimorelin – example of a growth hormone secretagogue.
  • Tretoquinol (trimetoquinol) – example of a beta-2 agonist.
  • 2-Androstenol, 3-Androstenol and 3-Androstenone – examples of substances related to 2-Androstenone.


Know your agents

  • The title of section 4.4 has changed from “Agents modifying myostatin function(s) including, but not limited, to: myostatin inhibitors” to “Agents preventing Activin receptor IIB activation”.
  • The following examples of prohibited substances have been added to reflect the ways in which the Activin receptor can be affected:
  • activin A-neutralizing antibodies
  • activin receptor IIB competitors such as decoy activin receptors (e.g. ACE-031)
  • anti-activin receptor IIB antibodies (e.g. bimagrumab)
  • myostatin inhibitors such as:
    1. agents reducing or ablating myostatin expression
    2. myostatin-binding proteins (e.g. follistatin, myostatin propeptide)
    3. myostatin-neutralizing antibodies (e.g. domagrozumab, landogrozumab, stamulumab)


Gene doping clarified

  • ‘Gene Doping’ has been changed to ‘Gene and Cell Doping’.
  • The definition of gene doping has changed to include the term ‘post-transcriptional’ to clearly define the processes that can be modified by gene editing.
  • Stem cells are not prohibited for treating injuries if their use restores normal function of the affected area, rather than enhancing function.


Cyclists: Be aware of tramadol

While WADA has elected to keep tramadol on the Monitoring List, rather than move it to the Prohibited List, the International Cycling Union (UCI) has announced plans to start testing athletes for tramadol from January. We are awaiting further information from UCI on this, but current reports indicate cyclists will have a finger pin-prick before a race, which detects the presence, or not, of tramadol and its level of concentration. This could lead to cyclists being banned from starting a race if they have used tramadol, primarily due to health concerns. We will update you when we know more.

The main changes to The Prohibited List for 2018 include:

Clarification regarding salbutamol inhaler dosing parameters

The dosing parameters of inhaled salbutamol have been clarified to make it clear that doses of salbutamol should not exceed 800 micrograms over any 12-hour period. Please refer to the WADA 2018 Summary of Major Modifications and Explanatory Notes for further information.


Glycerol to be removed from the List

Glycerol will no longer be prohibited in 2018 after being removed from the Diuretics and Masking Agents section of the List.

Changes to intravenous (IV) infusion rules

The allowed volume and timing of intravenous infusions will increase from infusions of no more than 50 millilitres (mL) per 6-hour period in 2017 to no more than a total of 100 mL per 12-hour period in 2018.

More specifically, IV infusions and/or injections of any substance in excess of 100 mL per 12-hour period will be prohibited at all times in 2018, except for those legitimately received in the course of hospital treatment, surgical procedures, or clinical diagnostic investigations. If a prohibited substance is administered intravenously or via injection, a TUE will continue to be necessary for this substance regardless of whether the infusion or injection is less than 100 mL.

Additional examples of stimulants

1,3-Dimethybutylamine (DMBA) will be added as an example of a stimulant under section 6 of the 2018 List. Athletes should remain vigilant regarding this substance as it can be found in some dietary supplements. UKAD’s position on dietary supplements can be found here.

Clarification regarding the status of cannabidiol

The WADA List Expert Group have confirmed that synthetic cannabidiol (i.e. CBD oil) is not a cannabimimetic and is therefore not prohibited under S8 Cannabinoids. However, athletes should be cautious about use of such products as cannabidiol extracted from cannabis plants may contain varying concentrations of THC (THC remains a prohibited substance).

Examples of glucocorticoids (S9) to be added

The 2018 Prohibited List will name some examples of commonly used glucocorticoids for greater clarity (refer to the 2018 List for further details).

Alcohol to be removed from the List

Alcohol will no longer be prohibited in 2018. The International Federations of Air Sports, Archery, Automobile, and Powerboating will be able to apply and enforce protocols for alcohol use as they see fit.

Specific examples of prohibited substances to be added to various categories of the List

Please refer to the WADA 2018 Summary of Major Modifications and Explanatory Notes document for these examples.


Team NI at Airport

Clean Games Policy 2017-2020


In April 2017 UK Anti-Doping launched the Clean Games Policy 2017-2020 for implementation through the Major Games Programme.  The Clean Games Policy was signed up to by the British Olympic Association, British Paralympic Association, Commonwealth Games England, Commonwealth Games Scotland, Commonwealth Games Wales and the Northern Ireland Commonwealth Games Council.  UK Anti-Doping, the home country sports councils and national governing bodies are responsible for the programme co-ordination and delivery. The objective of the Clean Games Policy is to prevent inadvertent doping at a Major Games by an athlete or athlete support personnel.  Under the policy, all long-listed and confirmed team members must complete their associated requirements of the Major Games Programme, and have evidence of completion, prior to attendance at the Games.


2018 Gold Coast Commonwealth Games


As part of the Major Games Programme, Sport Northern Ireland Pure Winner, in conjunction with UK Anti-Doping and the Northern Ireland Commonwealth Games Council, worked with the athletes and athlete support personnel who were qualified for and were selected to complete for Team NI at the 2018 Gold Coast Commonwealth Games to ensure they received up to date anti-doping education prior to travelling to the Gold Coast, as per the new Clean Games Policy.  This entailed working with 13 sports, 90 athletes and 46 coaches and support staff to ensure 100% of Team NI received their Clean Sport, Clean Games, Coach Clean and Advisor education.


Clean Sport education is tailored towards each individual athletes’ anti-doping knowledge but as a minimum provides information on a range of topics including:


  • What the Prohibited List is – including how and when it’s updated
  • How to check medication (including over the counter medications, e.g. lemsip etc)
  • Risks from supplements
  • What happens in a drug test
  • Anti-Doping Rule Violations – how many, what are they and the sanctions


All Team NI members received specific Gold Coast Clean Games education which included information on In-Competition dates, Therapeutic Use Exemptions (TUEs), whereabouts, drug testing at the Games and specific issues to be aware of when competing in Australia.


Post-Games monitoring revealed that 81% of Team NI rated our Clean Sport workshops as excellent and 97% stated they had gained new knowledge from the education programme.


UK Anti-Doping Supplement Warning

UK Anti-Doping cautions athletes and players in the UK to be aware of the prohibited substance 1, 3-dimethylbutylamine (DMBA) following its identification in a number of supplement products.

Read the full article…